Non-aqueous titrimetric assay of gabapentin in capsules using perchloric acid as titrant
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چکیده
منابع مشابه
titrimetriC aSSay of liSinopril in aqueouS and non-aqueouS media
Four simple titrimetric procedures are described for the determination of lisinopril (LNP) in bulk and in pharmaceuticals based on the neutralization of basic-amino and acidic carboxylic acid groups present in LNP. Method A is based on the neutralization of basic amino groups using perchloric acid as titrant in anhydrous acetic acid medium. Method B, method C and method D are based on neutraliz...
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Based on the nitrogenous base or tertiary amine moiety in zolmitriptan (ZMT), an anti-migraine drug, two highly accurate and selective titrimetric methods are proposed for the determination of ZMT in bulk drug and pharmaceuticals. In these methods, the drug dissolved in glacial acetic acid, was titrated with acetous perchloric acid and end point determined either visually by using crystal viole...
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An inexpensive, simple, precise and rapid method for the determination of fluoroquinolone gatifloxacin in tablets is described. The procedure is based on the use of volumetric dosage in a non-aqueous medium in glacial acetic acid with 0.1 M perchloric acid. The method validation yielded good results and included the precision, recovery and accuracy. It was also found that the excipients in the ...
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Hydroxyzine, a piperazine H1-receptor antagonists effective in generalized anxiety disorder. Two simple, rapid, reliable, precise and accurate and cost-effective non-aqueous titrimetric procedures have been developed for the determination of hydroxyzine dihydrochloride (HDH) in bulk drug and its pharmaceutical formulations. The methods are based on the titration of the drug in glacial acetic ac...
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Based on the nitrogenous base or quaternary ammonium moiety in isoxsuprine hydrochloride (ISX), two highly accurate and selective titrimetric methods are proposed f or the determination of ISX in spiked human urine, injection and tablets. Non aqueous titration (Method A) involves removal of protonated amine using mercuric acetate for enhanced basic nitrogen prior to titration with perchloric ac...
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ژورنال
عنوان ژورنال: Chemical Industry and Chemical Engineering Quarterly
سال: 2011
ISSN: 1451-9372,2217-7434
DOI: 10.2298/ciceq101011001a